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PDGFA‐associated protein 1 is a novel target of c‐Myc and contributes to colorectal cancer initiation and progression

18 Jun 2022

Abstract excerpt

BACKGROUND: The mechanism underlying colorectal cancer (CRC) initiation and progression remains elusive, and overall survival is far from satisfactory. Previous studies have shown that PDGFA-associated protein 1 (PDAP1) is upregulated in several cancers including CRC. Here, we aimed to identify the cause and consequence of PDAP1 dysregulation in CRC and evaluate its role as a potential therapeutic target....

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PMID: 35716012
DOI: 10.1002/cac2.12322

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