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Comparative genomic signatures in young and old Chinese patients with colorectal cancer.

Cancer medicine - 1 Jul 2021

Wang Fei, Cheng Huanqing, Zhang Xiao, Shan Lina, Bai Bingjun, Chen Kangke, Lou Feng, Cao Shanbo, Wang Huina, Dai Sheng

Abstract excerpt

BACKGROUND: Occurrence at a young age is known to be associated with unique clinical features in colorectal cancer (CRC). However, the genomic differences between young and old patients with CRC are not well elucidated and, to the best of our knowledge, have never been investigated in a Chinese population. METHODS: Tumor tissue samples from 29 young (age ≤50 years) and 46 old (age >50 years) patients with CRC...

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Identifiers

PMID: 34041865
DOI: 10.1002/cam4.3987
PMCID: PMC8267122

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