Article
[Clinicopathological features and prognosis of gastrointestinal stromal tumors with KIT/PDGFRA gene "homozygous mutation": a multicenter retrospective cohort study].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 25 Sept 2021
Shen Y Y, Li X Q, Yang L X, Fang Y, Nie M M, He Z R, Hou Y Y, Cao H, Wang M, Shen K T
Abstract excerpt
Objective: To investigate the clinicopathological features of gastrointestinal stromal tumor (GIST) with KIT/PDGFRA "homozygous mutation", the efficacy of targeted therapy and the prognosis. Methods: A retrospective cohort study and propensity score matching were used. "Homozygous mutation" was defined as the detection of KIT/PDGFRA gene status of GIST by Sanger sequencing, which showed that there was only mutant...
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