Article
Genomic profiling, prognosis, and potential interventional targets in young and old patients with cholangiocarcinoma.
Cancer biology & therapy - 31 Dec 2023
Wang Junhua, Shi Yaoting, Chen Jianbo, Liu Juying, Zhao Xiaotian, Pang Jiaohui, Sun Ximin, Tian Yichen, Ou Qiuxiang, Xia Feng, Chen Yunjie
Abstract excerpt
Molecular mechanisms behind potentially inferior prognosis of old cholangiocarcinoma (CCA) patients are unclear. Prevalence of interventional targets and the difference between young and old CCA patients are valuable for promising precision medicine. A total of 188 CCA patients with baseline tumor tissue samples were subgrouped into the young (≤45 years) and old (>45 years) sub-cohorts. Somatic and germline...
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