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Article

Identification of Human Norovirus GII.3 Blockade Antibody Epitopes.

Viruses - 13 Oct 2021

Yi Yufang, Wang Shuxia, Wang Xiaoli, Xiong Pei, Liu Qingwei, Zhang Chao, Yin Feifei, Huang Zhong

Abstract excerpt

Human noroviruses are a common pathogen causing acute gastroenteritis worldwide. Among all norovirus genotypes, GII.3 is particularly prevalent in the pediatric population. Here we report the identification of two distinct blockade antibody epitopes on the GII.3 capsid. We generated a panel of monoclonal antibodies (mAbs) from mice immunized with virus-like particle (VLP) of a GII.3 cluster 3 strain. Two of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34696487
DOI: 10.3390/v13102058
PMCID: PMC8539815

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