Article
Infant antibody and B-cell responses following confirmed pediatric GII.17 norovirus infections functionally distinguish GII.17 genetic clusters.
Frontiers in immunology - 1 Jan 2023
Strother Camilla A, Brewer-Jensen Paul D, Becker-Dreps Sylvia, Zepeda Omar, May Samantha, Gonzalez Fredman, Reyes Yaoska, McElvany Benjamin D, Averill April M, Mallory Michael L, Montmayeur Anna M, Costantini Verónica P, Vinjé Jan, Baric Ralph S, Bucardo Filemon, Lindesmith Lisa C, Diehl Sean A
Abstract excerpt
Genogroup II (GII) noroviruses are a major cause of diarrheal disease burden in children in both high- and low-income countries. GII.17 noroviruses are composed of distinct genetic clusters (I, II, IIIa, and IIIb) and have shown potential for replacing historically more prevalent GII.4 strains, but the serological basis for GII.17 antigenic diversity has not been studied in children. Utilizing samples from a...
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