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Article

Variable and conserved B cell epitopes of GII.4 human noroviruses.

Journal of virology - 17 Feb 2026

Parra Gabriel I, Ford-Siltz Lauren A, Pilewski Kelsey A, Tohma Kentaro, Landivar Michael, Kendra Joseph A

Abstract excerpt

Norovirus is a leading cause of acute gastroenteritis worldwide, imposing a major burden on public health and healthcare systems. Despite its significant medical impact, no licensed vaccines or specific antiviral therapies are currently available. Norovirus vaccine development is complicated by several factors, including the extreme genetic and antigenic diversity. In particular, the predominant genotype GII.4...

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Antigenic Variation
Caliciviridae Infections
Epitopes, B-Lymphocyte
Gastroenteritis
Genotype

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PMID: 41528130
DOI: 10.1128/jvi.01804-25
PMCID: PMC12911863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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