Article
Identification of a blockade epitope of human norovirus GII.17.
Emerging microbes & infections - 1 Dec 2021
Yi Yufang, Wang Xiaoli, Wang Shuxia, Xiong Pei, Liu Qingwei, Zhang Chao, Yin Feifei, Huang Zhong
Abstract excerpt
Human noroviruses are the dominant causative agent of acute viral gastroenteritis worldwide. During the winter of 2014-2015, genotype GII.17 cluster IIIb strains emerged as the leading cause of norovirus infection in Asia and later spread to other parts of the world. It is speculated that mutation at blockade epitopes may have resulted in virus escape from herd immunity, leading to the emergence of GII.17 cluster...
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