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Article

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis.

Biomolecules - 30 Sept 2021

Mäki-Nevala Satu, Ukwattage Sanjeevi, Wirta Erkki-Ville, Ahtiainen Maarit, Ristimäki Ari, Seppälä Toni T, Lepistö Anna, Mecklin Jukka-Pekka, Peltomäki Päivi

Abstract excerpt

Immunological and epigenetic changes are interconnected and contribute to tumorigenesis. We determined the immunoprofiles and promoter methylation of inflammation-related genes for colitis-associated colorectal carcinomas (CA-CRC). The results were compared with Lynch syndrome (LS)-associated colorectal tumors, which are characterized by an active immune environment through inherited mismatch repair defects....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34680073
DOI: 10.3390/biom11101440
PMCID: PMC8533626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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