Article
Prognostic implication of CD274 (PD-L1) protein expression in tumor-infiltrating immune cells for microsatellite unstable and stable colorectal cancer.
Cancer immunology, immunotherapy : CII - 1 Jul 2017
Lee Kyu Sang, Kwak Yoonjin, Ahn Soyeon, Shin Eun, Oh Heung-Kwon, Kim Duck-Woo, Kang Sung-Bum, Choe Gheeyoung, Kim Woo Ho, Lee Hye Seung
Abstract excerpt
In this study, we investigated the clinical relevance of CD274 (PD-L1) protein expression by tumor cells and tumor-infiltrating immune cells in colorectal cancer (CRC). To this end, 186 microsatellite instability-high (MSI-H) and 153 microsatellite stable (MSS) CRCs were subjected to immunohistochemistry (IHC) analysis for the expression of CD274 and mismatch repair proteins. CD274 expression was evaluated in...
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