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Article

Associating complex traits with genetic variants: polygenic risk scores, pleiotropy and endophenotypes.

Genetica - 1 Aug 2022

Fisch Gene S

Abstract excerpt

Genotype-phenotype causal modeling has evolved significantly since Johannsen's and Wright's original designs were published. The development of genomewide assays to interrogate and detect possible causal variants associated with complex traits has expanded the scope of genotype-phenotype research considerably. Clusters of causal variants discovered by genomewide assays and associated with complex traits have been...

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Identifiers

PMID: 34677750
DOI: 10.1007/s10709-021-00138-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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