Article
Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine.
Trends in genetics : TIG - 1 Aug 2016
Hall Molly A, Moore Jason H, Ritchie Marylyn D
Abstract excerpt
Genome-wide association studies (GWAS) have identified numerous loci associated with human phenotypes. This approach, however, does not consider the richly diverse and complex environment with which humans interact throughout the life course, nor does it allow for interrelationships between genetic loci and across traits. As we move toward making precision medicine a reality, whereby we make predictions about...
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