Article
Polygenic Epidemiology.
Genetic epidemiology - 1 May 2016
Dudbridge Frank
Abstract excerpt
Much of the genetic basis of complex traits is present on current genotyping products, but the individual variants that affect the traits have largely not been identified. Several traditional problems in genetic epidemiology have recently been addressed by assuming a polygenic basis for disease and treating it as a single entity. Here I briefly review some of these applications, which collectively may be termed...
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