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Article

Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Jan 2006

Wang Yanchang, Ng Tuen-Yung

Abstract excerpt

In budding yeast Saccharomyces cerevisiae, Cdc5 kinase is a component of mitotic exit network (MEN), which inactivates cyclin-dependent kinase (CDK) after chromosome segregation. cdc5-1 mutants arrest at telophase at the nonpermissive temperature due to the failure of CDK inactivation. To identify more negative regulators of MEN, we carried out a genetic screen for genes that are toxic to cdc5-1 mutants when...

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Identifiers

PMID: 16079183
DOI: 10.1091/mbc.e04-12-1109
PMCID: PMC1345648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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