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Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival

13 Oct 2021

Abstract excerpt

Better understanding of GBM signalling networks in-vivo would help develop more physiologically relevant ex vivo models to support therapeutic discovery. A "functional proteomics" screen was undertaken to measure the specific activity of a set of protein kinases in a two-step cell-free biochemical assay to define dominant kinase activities to identify potentially novel drug targets that may have been overlooked...

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PMID: 34645618
DOI: 10.26508/lsa.202101054

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