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Article

Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2014

Cassol Clarissa A, Winer Daniel, Liu Wei, Guo Miao, Ezzat Shereen, Asa Sylvia L

Abstract excerpt

Pheochromocytomas and paragangliomas are neuroendocrine tumors shown to be responsive to multitargeted tyrosine kinase inhibitor (TKI) treatment. Despite growing knowledge regarding their genetic basis, the ability to predict behavior in these tumors remains challenging. There is also limited knowledge of their tyrosine kinase receptor expression and whether the clinical response observed to the TKI sunitinib...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24390213
DOI: 10.1038/modpathol.2013.233
PMCID: PMC4977182

Genes

KIT
FGFR3
FGFR1
FGFR2
FGFR4
MIB1
SDHB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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