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Article

A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score.

Translational psychiatry - 17 Jan 2017

Ciuculete D M, Boström A E, Voisin S, Philipps H, Titova O E, Bandstein M, Nikontovic L, Williams M J, Mwinyi J, Schiöth H B

Abstract excerpt

Genome-wide association studies have identified a number of single-nucleotide polymorphisms (SNPs) that are associated with psychiatric diseases. Increasing body of evidence suggests a complex connection of SNPs and the transcriptional and epigenetic regulation of gene expression, which is poorly understood. In the current study, we investigated the interplay between genetic risk variants, shifts in methylation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28094813
DOI: 10.1038/tp.2016.275
PMCID: PMC5545735

Genes

GAD1
DIAPH1
FKBP5
HCRTR1
HDAC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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