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Article

A multi-omics study of brain tissue transcription and DNA methylation revealing the genetic pathogenesis of ADHD.

Briefings in bioinformatics - 23 Sept 2024

Wang Jingkai, Zhu Qiu-Wen, Mai Jia-Hao, Zhang Shun, Wang Yuqing, Liang Jiatong, Zhou Ji-Yuan

Abstract excerpt

Attention-deficit/hyperactivity disorder (ADHD) is a chronic psychiatric disease that often affects a patient's whole life. Research has found that genetics plays an important role in the development of ADHD. However, there is still a lack of knowledge about the tissue-specific causal effects of biological processes beyond gene expression, such as alternative splicing (AS) and DNA methylation (DNAm), on ADHD. In...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39406522
DOI: 10.1093/bib/bbae502
PMCID: PMC11479714

Genes

COMMD5
GGT7
HYAL3
TREM2

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