Article

Exploring Genetic Variation that Influences Brain Methylation in Attention-Deficit/Hyperactivity Disorder

2018-09-10

Abstract excerpt

<h4>ABSTRACT</h4> Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder caused by an interplay of genetic and environmental factors. Epigenetics is crucial to lasting changes in gene expression in the brain. Recent studies suggest a role for DNA methylation in ADHD. We explored the contribution to ADHD of allele-specific methylation (ASM), an epigenetic mechanism that involves SNPs corr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9bede59e-23e8-5054-a461-4719a7dff2ef
DOI: 10.1101/413005

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring Genetic Variation that Influences Brain Methylation in Attention-Deficit/Hyperactivity DisorderDOI 10.1101/413005Read

Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorderSemantic proximity Read

Epigenome-wide association study of attention-deficit/hyperactivity disorder in adultsSemantic proximity Read

Large epigenome-wide association study of childhood ADHD identifies peripheral DNA methylation associated with disease and polygenic risk burdenSemantic proximity Read

A multi-omics study of brain tissue transcription and DNA methylation revealing the genetic pathogenesis of ADHD.Semantic proximity Read

Identification of genetic variants influencing methylation in brain with pleiotropic effects on psychiatric disorders.Semantic proximity Read

Epigenetics and ADHD: Reflections on Current Knowledge, Research Priorities and Translational PotentialSemantic proximity Read

Discovery of the first genome-wide significant risk loci for ADHDSemantic proximity Read

Cortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorderSemantic proximity Read

Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children.Semantic proximity Read

DNA Methylation in LIME1 and SPTBN2 Genes Is Associated with Attention Deficit in ChildrenSemantic proximity Read

Insights into attention-deficit/hyperactivity disorder from recent genetic studies.Semantic proximity Read

Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation.Semantic proximity Read