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Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder

3 Oct 2019

Abstract excerpt

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder caused by an interplay of genetic and environmental factors. Epigenetics is crucial to lasting changes in gene expression in the brain. Recent studies suggest a role for DNA methylation in ADHD. We explored the contribution to ADHD of allele-specific methylation (ASM), an epigenetic mechanism that involves SNPs correlating with...

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PMID: 31582733
DOI: 10.1038/s41398-019-0574-7

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