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Article

Overlapping common genetic architecture between major depressive disorders and anxiety and stress-related disorders.

Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2022

Mei Liwei, Gao Yan, Chen Min, Zhang Xiao, Yue Weihua, Zhang Dai, Yu Hao

Abstract excerpt

Major depressive disorders (MDDs) and anxiety and stress-related disorders (ASRDs) have overlapping symptoms and high rates of comorbidity. However, the underlying mechanisms remain largely unknown. Here, we aimed to examine whether MDD and ASRD share genetic risk factors utilizing recent large-scale genome-wide association studies (GWASs). To examine the genetic overlap between MDD and ASRD, we applied genetic...

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Identifiers

PMID: 34634379
DOI: 10.1016/j.pnpbp.2021.110450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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