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Article

Phenotypic change of the transplantable MXT mammary adenocarcinoma into mixed bone producing sarcoma-like tumors.

Anticancer research - 1 Jan 2000

Kiss R, Devleeschouwer N, Paridaens R J, Danguy A, Heuson J C, Atassi G

Abstract excerpt

The B6D2F1 mouse mammary adenocarcinoma was adapted to grow in vitro as monolayer. After in vitro passaging of tumor cells, phenotypic changes occurred that were expressed in vivo. Following intraperitoneal inoculation of tumor cells, bone-forming tumors developed. These tumors consisted of undifferentiated adenocarcinoma mixed with large amount of cartilagenous and osseous tissue. The etiology of these...

Topics

Adenocarcinoma
Animals
Autoradiography
Cold Temperature
Female
Mammary Neoplasms, Experimental
Mice
Mice, Inbred Strains
Neoplasm Transplantation
Neoplasms, Hormone-Dependent
Osteogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Osteosarcoma

Phenotype

Receptors, Estrogen

Receptors, Progesterone

Tissue Preservation

Source

Identifiers

PMID: 3463244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3463244-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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