Article
Association of hst gene expression with metastatic phenotype in mouse mammary tumors.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 May 1990
Murakami A, Tanaka H, Matsuzawa A
Abstract excerpt
From the pregnancy-dependent mouse mammary tumor TPDMT-4, four autonomous sublines were established after its independent progression under different conditions. Despite their similar growth rates in inguinal fat pads, three sublines formed lung metastases, and one did not when they were injected i.v. into mice as a single cell suspension. The TPDMT-4 tumor and the nonmetastatic subline expressed mRNA for the orf...
Topics
- Adipose Tissue
- Animals
- Female
- Fibroblast Growth Factor 3
- Fibroblast Growth Factor 4
- Fibroblast Growth Factors
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Genes, Viral
- Growth Substances