Osteomimicry: how tumor cells try to deceive the bone.

doi:10.2741/s110

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Article

Osteomimicry: how tumor cells try to deceive the bone.

Frontiers in bioscience (Scholar edition) - 1 Jun 2010

Rucci Nadia, Teti Anna

Abstract excerpt

Bone metastases are complications of multiple myeloma and solid tumors, including breast and prostate carcinomas. Several reports have demonstrated that the preference to metastasize to bone by tumor cells is not a casual but an addressed event, which relies on specific interactions among tumor cells, bone marrow microenvironment and bone cells. One of the features that gives tumor cells more chances to survive...

Topics

Alkaline Phosphatase
Bone Matrix
Bone Morphogenetic Proteins
Bone Neoplasms
Breast Neoplasms
Core Binding Factor Alpha 1 Subunit
Endothelin-1
Female
Humans
Male
Models, Biological
Osteoblasts
Osteolysis
Phenotype
Prostatic Neoplasms
Signal Transduction
Urokinase-Type Plasminogen Activator
Wnt Proteins

Source

Open in PubMed

Identifiers

PMID: 20515833
DOI: 10.2741/s110

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