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KIF20A Promotes CRC Progression and the Warburg Effect through the C-Myc/HIF-1α Axis

1 Dec 2023

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a prevalent form of cancer globally, characterized by a high mortality rate. Therefore, discovering effective therapeutic approaches for CRC treatment is critical. METHODS: The levels of KIF20A in CRC clinical samples were determined using Western Blot and immunofluorescence assay. SW480 cells were transfected with siRNA targeting KIF20A, while HT-29 cells were transfected...

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PMID: 38037834
DOI: 10.2174/0109298665256238231120093150

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