Article

Tumor Budding-Derived CCL5 Recruits Fibroblasts to Promote Colorectal Cancer Progression Through CCR5-SLC25A24 Signaling

2021-10-19

Abstract excerpt

<h4>Background: </h4> Tumor buddings have been included in the routine diagnosis of colorectal cancer (CRC) and considered to be a tumor prognostic factor independent of TNM staging. This study aimed at identifying the contribution of tumor budding-derived C-C chemokine ligand 5 (CCL5) to tumor microenvironment (TME) through fibroblasts. <h4>Methods: </h4>: Co-cultivation recruitment assays and human cytokine arra...

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Literature Corpus work: fe2d2b25-641c-5cfb-b979-785b7ce73caa
DOI: 10.21203/rs.3.rs-961545/v1

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