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Disparities in Gallbladder Cancer: Epidemiology, Molecular Mechanisms, and Clinical Implications.

Molecular biology reports - 19 May 2026

Sahoo Om Saswat, Gill Gurpeet Singh, Nayek Arnab, Bhardwaj Nidhi, Kurdia Kailash Chand, Galodha Saurabh, Chetan R, Dhar Ruby, Karmakar Subhradip

Abstract excerpt

Gallbladder cancer (GBC) is a rare yet highly aggressive malignancy and remains the most prevalent cancer of the biliary tract. The pathogenesis is multifactorial, involving chronic inflammation, gallstone disease, genetic predisposition, and environmental and lifestyle determinants. Notably, GBC exhibits pronounced disparities across multiple dimensions, including sex, geography, ethnicity, and others which...

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PMID: 42154094
DOI: 10.1007/s11033-026-11975-9

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