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Article

Association of potentially functional genetic variants of PLCE1 with gallbladder cancer susceptibility in north Indian population.

Journal of gastrointestinal cancer - 1 Dec 2013

Sharma Kiran Lata, Umar Meenakshi, Pandey Manmohan, Misra Sanjeev, Kumar Ashok, Kumar Vijay, Mittal Balraj

Abstract excerpt

BACKGROUND AND OBJECTIVES: Phospholipase C epsilon 1 (PLCE1) plays crucial roles in carcinogenesis and progression of esophageal and gastric cancers. In the present study, we investigated association of GWAS identified rs2274223 A>G and. rs7922612 T>C polymorphism of PLCE1 with susceptibility to gallbladder cancer (GBC). METHODS: The study involved genotyping of selected PLCE1 variants in 416 GBC cases and 225...

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PMID: 23975622
DOI: 10.1007/s12029-013-9537-z

Genes

PLCE1

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Association of potentially functional genetic variants of PLCE1 with gallbladder cancer susceptibility in north Indian population.PMID 23975622Read ↗

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Phospholipase C epsilon 1 (PLCE1 rs2274223A>G, rs3765524C>T and rs7922612C>T) polymorphisms and esophageal cancer risk in the Kashmir Valley.Semantic proximity Read ↗

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