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Article

Combinations of SERPINB5 gene polymorphisms and environmental factors are associated with oral cancer risks.

PloS one - 1 Jan 2017

Tsai Hsiu-Ting, Hsieh Ming-Ju, Lin Chiao-Wen, Su Shih-Chi, Miao Nae-Fang, Yang Shun-Fa, Huang Hui-Chuan, Lai Fu-Chih, Liu Yu-Fan

Abstract excerpt

BACKGROUND: We identified rs17071138 T/C, rs3744941 C/T, and rs8089104 T/C gene polymorphisms of SERPINB5 (mammary serine protease inhibitor) that are specific to patients with oral cancer susceptibility and their clinicopathological status. METHODOLOGY/PRINCIPAL FINDINGS: In total, 1342 participants, including 601 healthy controls and 741 patients with oral cancer, were recruited for this study. Allelic...

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Identifiers

PMID: 28339463
DOI: 10.1371/journal.pone.0163369
PMCID: PMC5365097

Genes

SERPINB5

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