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Functional relevance of MMP2 promoter variants in gallbladder cancer: A case-control study in an Eastern Indian Population.

Gene - 30 Jun 2024

Jeeyar Vinay, Prasad Singh Shivaram, Dixit Manjusha

Abstract excerpt

Gallbladder cancer (GBC) is a prevalent and deadly form of bile duct cancer, associated with poor prognosis. This study aimed to investigate the genetic factors contributing to the high incidence of GBC in certain geographical regions, particularly in the Northern and Eastern parts of India. The present case-control study focused on MMP2, a gene involved in tumor progression and metastasis, as a potential...

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PMID: 38499214
DOI: 10.1016/j.gene.2024.148372

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