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Defining Baseline Mechanisms of Cefiderocol Resistance in the Enterobacterales

7 Oct 2021

Abstract excerpt

The objective of this study was to identify putative mechanisms contributing to baseline cefiderocol resistance among carbapenem-resistant Enterobacterales (CRE). We evaluated 56 clinical CRE isolates with no previous exposure to cefiderocol. Cefiderocol and comparator agent minimum inhibitory concentrations (MICs) were determined by broth microdilution. Short-read and/or long-read whole genome sequencing was...

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PMID: 34619049
DOI: 10.1089/mdr.2021.0095

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