Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE).

doi:10.1586/14787210.2016.1106940

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Article

Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE).

Expert review of anti-infective therapy - 1 Jan 2016

Goodman K E, Simner P J, Tamma P D, Milstone A M

Abstract excerpt

The Centers for Disease Control and Prevention (CDC) defines carbapenem-resistant Enterobacteriaceae (CRE) based upon a phenotypic demonstration of carbapenem resistance. However, considerable heterogeneity exists within this definitional umbrella. CRE may mechanistically differ by whether they do or do not produce carbapenemases. Moreover, patients can acquire CRE through multiple pathways: endogenously through...

Topics

Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
Communicable Disease Control
Cross Infection
Enterobacteriaceae
Enterobacteriaceae Infections
Epidemiological Monitoring
Gene Expression
Gene Transfer, Horizontal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Epidemiology

Mutation

Plasmids

United States

beta-Lactam Resistance

beta-Lactamases

Source

Open in PubMed

Identifiers

PMID: 26535959
DOI: 10.1586/14787210.2016.1106940

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