Article
Sensitivity of two SARS-CoV-2 variants with spike protein mutations to neutralising antibodies.
Virus genes - 1 Dec 2021
Müller Katharina, Girl Philipp, Giebl Andreas, Gruetzner Stefanie, Antwerpen Markus, Khatamzas Elham, Wölfel Roman, von Buttlar Heiner
Abstract excerpt
SARS-CoV-2 infections elicit a humoral immune response capable of neutralising the virus. However, multiple variants have emerged with mutations in the spike protein amongst others, the key target of neutralising antibodies. We evaluated the neutralising efficacy of 89 serum samples from patients, infected with SARS-CoV-2 in the beginning of 2020, against two virus variants isolated from acutely infected patients...
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