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Article

Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies.

PLoS pathogens - 1 Aug 2021

Alenquer Marta, Ferreira Filipe, Lousa Diana, Valério Mariana, Medina-Lopes Mónica, Bergman Marie-Louise, Gonçalves Juliana, Demengeot Jocelyne, Leite Ricardo B, Lilue Jingtao, Ning Zemin, Penha-Gonçalves Carlos, Soares Helena, Soares Cláudio M, Amorim Maria João

Abstract excerpt

Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin-converting enzyme 2 (ACE2) recognition, a function of the viral protein spike. Mutations in spike impacting antibody and/or ACE2 binding are appearing worldwide, imposing the need to monitor SARS-CoV2 evolution and dynamics in the population....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 34352039
DOI: 10.1371/journal.ppat.1009772
PMCID: PMC8341613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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