Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutralising antibody escape of SARS-CoV-2 spike protein: Risk assessment for antibody-based Covid-19 therapeutics and vaccines.

Reviews in medical virology - 1 Nov 2021

Focosi Daniele, Maggi Fabrizio

Abstract excerpt

The Spike protein is the target of both antibody-based therapeutics (convalescent plasma, polyclonal serum, monoclonal antibodies) and vaccines. Mutations in Spike could affect efficacy of those treatments. Hence, monitoring of mutations is necessary to forecast and readapt the inventory of therapeutics. Different phylogenetic nomenclatures have been used for the currently circulating SARS-CoV-2 clades. The Spike...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COVID-19 Vaccines

Share to Immune Evasion

Share to Immunization, Passive

Share to SARS-CoV-2

Share to South Africa

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 33724631
DOI: 10.1002/rmv.2231
PMCID: PMC8250244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutralising antibody escape of SARS-CoV-2 spike protein: Risk assessment for antibody-based Covid-19 therapeutics and vaccines.PMID 33724631Read ↗

Spike protein of SARS-CoV-2 variants: a brief review and practical implications.Semantic proximity Read ↗

SARS-CoV-2 Mutations and Their Impact on Diagnostics, Therapeutics and VaccinesSemantic proximity Read ↗

Structural and antigenic variations in the spike protein of emerging SARS-CoV-2 variants.Semantic proximity Read ↗

Immune Evasion of SARS-CoV-2 Emerging Variants: What Have We Learnt So Far?Semantic proximity Read ↗

ESC - a comprehensive resource for SARS-CoV-2 immune escape variantsSemantic proximity Read ↗

SARS-CoV-2 variants, spike mutations and immune escape.Semantic proximity Read ↗

Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity.Semantic proximity Read ↗

Structural Insights into the SARS-CoV-2 Spike Protein and Its Implications for Antibody Resistance.Semantic proximity Read ↗

Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects.Semantic proximity Read ↗

Molecular Level Dissection of Critical Spike Mutations in SARS‐CoV‐2 Variants of Concern (VOCs): A Simplified ReviewSemantic proximity Read ↗

ESC: a comprehensive resource for SARS-CoV-2 immune escape variants.Semantic proximity Read ↗

SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usageSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.