Article
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.
Nature - 1 May 2021
Wang Pengfei, Nair Manoj S, Liu Lihong, Iketani Sho, Luo Yang, Guo Yicheng, Wang Maple, Yu Jian, Zhang Baoshan, Kwong Peter D, Graham Barney S, Mascola John R, Chang Jennifer Y, Yin Michael T, Sobieszczyk Magdalena, Kyratsous Christos A, Shapiro Lawrence, Sheng Zizhang, Huang Yaoxing, Ho David D
Abstract excerpt
The COVID-19 pandemic has had widespread effects across the globe, and its causative agent, SARS-CoV-2, continues to spread. Effective interventions need to be developed to end this pandemic. Single and combination therapies with monoclonal antibodies have received emergency use authorization1-3, and more treatments are under development4-7. Furthermore, multiple vaccine constructs have shown promise8, including...
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