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Article

Enzyme modification using mutation site prediction method for enhancing the regioselectivity of substrate reaction sites.

Scientific reports - 4 Oct 2021

Ikebe Jinzen, Suzuki Munenori, Komori Aya, Kobayashi Kaito, Kameda Tomoshi

Abstract excerpt

Enzymes with low regioselectivity of substrate reaction sites may produce multiple products from a single substrate. When a target product is produced industrially using these enzymes, the production of non-target products (byproducts) causes adverse effects such as increased processing costs for purification and the amount of raw material. Thus it is required the development of modified enzymes to reduce the...

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Identifiers

PMID: 34602611
DOI: 10.1038/s41598-021-98433-7
PMCID: PMC8488038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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