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Article

MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes.

Database : the journal of biological databases and curation - 1 Jan 2012

Braun Andreas, Halwachs Bettina, Geier Martina, Weinhandl Katrin, Guggemos Michael, Marienhagen Jan, Ruff Anna J, Schwaneberg Ulrich, Rabin Vincent, Torres Pazmiño Daniel E, Thallinger Gerhard G, Glieder Anton

Abstract excerpt

Mutational events as well as the selection of the optimal variant are essential steps in the evolution of living organisms. The same principle is used in laboratory to extend the natural biodiversity to obtain better catalysts for applications in biomanufacturing or for improved biopharmaceuticals. Furthermore, single mutation in genes of drug-metabolizing enzymes can also result in dramatic changes in...

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Identifiers

PMID: 22730453
DOI: 10.1093/database/bas028
PMCID: PMC3381223

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Source receipt: pubmed, retrieved 7 Sept 2026.

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