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Article

Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants.

Molecules (Basel, Switzerland) - 11 Jun 2016

Liu Xing, Wang Zhi-Biao, Wang Ya-Nan, Kong Jian-Qiang

Abstract excerpt

M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation. With the aim of obtaining more hydroxylated steroid precursors it is necessary to probe the steroidal substrate diversity of these BM3 variants. Here, three...

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Source

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Identifiers

PMID: 27294908
DOI: 10.3390/molecules21060760
PMCID: PMC6273762

Genes

TES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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