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Article

LTA4H Prevalence and Mortality in Adult Zambians with Tuberculous Meningitis.

Annals of neurology - 1 Dec 2021

Siddiqi Omar K, Ghebremichael Musie, Musukuma Kalo, Dang Xin, Mubanga Eugene, Birbeck Gretchen L, Love Shawn, Buback Clayton, Kosloff Barry, Ayles Helen, Atadzhanov Masharip, Koralnik Igor J

Abstract excerpt

We conducted a prospective cohort study to determine the prevalence of leukotriene A4 hydrolase (LTA4H) polymorphisms in Zambian adults with tuberculous meningitis (TBM) and its association with mortality. We completed genotype testing on 101 definite cases of TBM and 119 consecutive non-TBM controls. The distribution of genotypes among TBM patients was as follows: C/C (0.83), C/T (0.14), T/T (0.03). There was no...

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Share to Epoxide Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34595756
DOI: 10.1002/ana.26240
PMCID: PMC13273832

Genes

LTA4H

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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