Article
Clinical Parameters, Routine Inflammatory Markers, and LTA4H Genotype as Predictors of Mortality Among 608 Patients With Tuberculous Meningitis in Indonesia.
The Journal of infectious diseases - 1 Apr 2017
van Laarhoven Arjan, Dian Sofiati, Ruesen Carolien, Hayati Ela, Damen Michelle S M A, Annisa Jessi, Chaidir Lidya, Ruslami Rovina, Achmad Tri Hanggono, Netea Mihai G, Alisjahbana Bachti, Rizal Ganiem Ahmad, van Crevel Reinout
Abstract excerpt
Background: Damaging inflammation is thought to contribute to the high morbidity and mortality of tuberculous meningitis (TBM), but the link between inflammation and outcome remains unclear. Methods: We performed prospective clinical and routine laboratory analyses of a cohort of adult patients with TBM in Indonesia. We also examined the LTA4H promoter polymorphism, which predicted cerebrospinal fluid (CSF)...
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