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Article

The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis.

Frontiers in immunology - 1 Jan 2024

Jian Yi, Bao Yuhang, Yang Fashuang, Zhu Mei

Abstract excerpt

Background: Tuberculous meningitis (TBM) is a non-purulent inflammatory condition affecting the meninges and spinal membranes, caused by Mycobacterium tuberculosis (MTB) infection. This study seeks to explore the impact of varying INH dosages and NAT2 gene polymorphisms on TBM treatment, contributing new insights to improve clinical management and patient prognosis. Methods: Patients with TBM hospitalized between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Isoniazid

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Share to Polymorphism, Genetic

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Source

Open in PubMed Open full text

Identifiers

PMID: 39902038
DOI: 10.3389/fimmu.2024.1535447
PMCID: PMC11788379

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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