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A Bayesian analysis of the association between <i>Leukotriene A4 Hydrolase</i> genotype and survival probability of tuberculous meningitis patients treated with adjunctive dexamethasone

2020-08-03

Abstract excerpt

Tuberculous meningitis (TBM) remains the most devastating form of tuberculosis (TB) with high mortality despite effective antimicrobial treatment. As mortality has been linked to excessive inflammation, anti-inflammatory glucocorticoids are now routinely used as adjunctive treatment with antimicrobial therapy. However, they reduce mortality by only ~ 30%, raising the possibility that only a subset of TBM deaths ar...

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Literature Corpus work
f248ed2c-13ee-58c4-b270-ffc1305a2abf
DOI
10.1101/2020.08.03.233791
Open publication

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A Bayesian analysis of the association between <i>Leukotriene A4 Hydrolase</i> genotype and survival probability of tuberculous meningitis patients treated with adjunctive dexamethasoneDOI 10.1101/2020.08.03.233791
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