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Article

Downregulated TNF-α Levels after Cryo-Thermal Therapy Drive Tregs Fragility to Promote Long-Term Antitumor Immunity.

International journal of molecular sciences - 15 Sept 2021

Lou Yue, Wang Junjun, Peng Peng, Wang Shicheng, Liu Ping, Xu Lisa X

Abstract excerpt

Immunotherapy has emerged as a therapeutic pillar in tumor treatment, but only a minority of patients get benefit. Overcoming the limitations of immunosuppressive environment is effective for immunotherapy. Moreover, host T cell activation and longevity within tumor are required for the long-term efficacy. In our previous study, a novel cryo-thermal therapy was developed to improve long-term survival in B16F10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34576115
DOI: 10.3390/ijms22189951
PMCID: PMC8468796

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