Article

Intratumoral administration of mRNA-1273 vaccine delays melanoma growth in mice

2024-05-10

Abstract excerpt

<h4>Background</h4> Immunotherapies are advantageous for treating cancers; however, their efficacy is limited in unresponsive hosts with “cold” tumor microenvironments. This limitation primarily stems from the lack of infiltrating CD8 + T cells, which are major effectors of the anti-cancer immune response. Here, we demonstrate the effects of intratumoral (IT) injections of the COVID-19 mRNA vaccine on the impair...

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Literature Corpus work: 57d41448-2005-5e31-bc45-bfb149a80580
DOI: 10.1101/2024.05.06.592840

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