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DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

17 Mar 2022

Abstract excerpt

DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA methylation were suggested to be useful biomarkers for diagnosis, and for the determination of prognosis and treatment response. Here, we provide an overview of methylation-based biomarkers in colorectal cancer. First, we start with the two methylation-based diagnostic biomarkers already approved for colorectal cancer, SEPT9 and...

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PMID: 35307512
DOI: 10.1016/j.bbcan.2022.188722

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