Article
Identification and functional validation of HLA-C as a potential gene involved in colorectal cancer in the Korean population.
BMC genomics - 4 Apr 2022
Lim Eun Bi, Oh Ho-Suk, Kim Kang Chang, Kim Moon-Ho, Kim Young Jin, Kim Bong Jo, Nho Chu Won, Cho Yoon Shin
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide and is influenced by environmental and genetic factors. Although numerous genetic loci for CRC have been identified, the overall understanding of the genetic factors is yet to be elucidated. We sought to discover new genes involved in CRC applying genetic association analysis and functional study. RESULTS: We conducted exome array...
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