Article
Impact of mini-driver genes in the prognosis and tumor features of colorectal cancer samples: a novel perspective to support current biomarkers.
PeerJ - 1 Jan 2023
Campos Segura Anthony Vladimir, Velásquez Sotomayor Mariana Belén, Gutiérrez Román Ana Isabel Flor, Ortiz Rojas César Alexander, Murillo Carrasco Alexis Germán
Abstract excerpt
Background: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths, and its development is associated with the gains and/or losses of genetic material, which leads to the emergence of main driver genes with higher mutational frequency. In addition, there are other genes with mutations that have weak tumor-promoting effects, known as mini-drivers, which could aggravate the development of...
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