Article
SNPs previously associated with Dupuytren's disease replicated in a North American cohort.
Clinical medicine & research - 1 Dec 2014
Anderson Eric R, Ye Zhan, Caldwell Michael D, Burmester James K
Abstract excerpt
OBJECTIVE: Dupuytren's disease is a progressive fibrosis of the hand that often results in debilitating flexion contractures. Its etiology is not completely understood but likely involves both genetic and environmental factors. A recent study performed in Europe identified DNA variants that associate with Dupuytren's disease. Given the likelihood for genetic variation among populations, we planned to validate the...
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