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Article

WNT2 locus is involved in genetic susceptibility of Peyronie's disease.

The journal of sexual medicine - 1 May 2012

Dolmans Guido H, Werker Paul M, de Jong Igle J, Nijman Rien J, Wijmenga Cisca, Ophoff Roel A

Abstract excerpt

INTRODUCTION: Peyronie's disease (PD) is a fibromatosis of the penis, with a pathology very similar to what is seen in the hand (palmar fascia) in Dupuytren's disease (DD). Recently, we performed a genome-wide association study and identified nine genetic loci containing common variants associated with DD. Seven of these loci mapped within or near genes of the canonical WNT pathway and each locus yielded...

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Source

Identifiers

PMID: 22489561
DOI: 10.1111/j.1743-6109.2012.02704.x

Genes

WNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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